Big data, machine learning, deep learning, computer assisted human learning, preference learning, automated reasoning, decision making and multi-agent systems play a key role in the challenges LIP6 tackles. Our goal is to push forward the current state-of-the-art to: (i) elaborate techniques and tools that scale up enough to increase their impact in computer science and in other scientific fields, (ii) enter in the era where decisions/recommendations made by AI to end-users are justified, and (iii) manage imprecision, uncertainty and context change over time.